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- We have developed a computer database containing information on over 1,000
- human hypoxanthine guanine phosphoribosyl transferase (HPRT) mutants. Both
- published and unpublished data are present. The database itself is
- maintained in a dBASE format (.DBF) and we provide a set of programs to
- examine and extract information from the database. A program to input
- information into the database is also supplied. The database and programs
- are available directly from us or via remote FTP (file transfer protocol)
- using BITNET/INTERNET. All programs require an IBM-compatible computer, the
- MS-DOS operating system (version 3.3 or greater), and a hard disk with
- about 5 megabytes of free disk space. The purpose of the database is 1) to
- allow investigators to contribute their HPRT mutants directly to the
- database in a standardized fashion, and 2) to allow access to the entire
- database with a set of programs that allows manipulation and extraction of
- data. For example, using our programs it is possible to i) order the
- database by base pair position, ii) examine only information regarding
- mutagenesis by a particular agent, iii) search for a particular author, iv)
- create a report which contains selected portions of the database, the
- report can be printed or saved as a file. The database will be updated
- every several months and distributed.
-